Dell XPS 10 with Windows RT gets major price cut: base model now $300

We don't know for sure that Dell's been experiencing the weak demand for Windows RT Samsung's been so vocal about, but significant price cuts to its XPS 10 tablet hybrid suggest it hasn't exactly been flying off the shelves. Not only has the $500 tag for the tablet with 32GB of storage dropped to $300, but adding another 32GB now only costs $50 more, instead of $100. Savings have extended to the keyboard dock, too -- opting for the bundle used to increase the overall cost by $180, but now that peripheral is only a $50 extra. (Make sure to lead with the bundle though, as it's $100 if added from the tablet-only customization options). The cost of optional LTE hasn't changed, however, so that 4G radio still costs an additional $100. While we haven't reached fire sale territory just yet, the cuts are still a welcome discount for consumers. In the interest of preserving profit margins, perhaps Dell should ask Acer's president to consult next time it's cooking up new hardware.

Filed under: Laptops, Tablets, Dell

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Source: http://www.engadget.com/2013/05/15/dell-xps-10-price-cut/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Video: Hundreds Flee Southern California Wildfire

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Taking cholesterol-lowering drugs may also reduce the risk of dying from prostate cancer

May 1, 2013 ? Men with prostate cancer who take cholesterol-lowering drugs called statins are significantly less likely to die from their cancer than men who don't take such medication, according to study led by researchers at Fred Hutchinson Cancer Research Center. The findings are published online today in The Prostate.

The study, led by Janet L. Stanford, Ph.D., co-director of the Prostate Cancer Research Program and a member of the Hutchinson Center's Public Health Sciences Division, followed about 1,000 Seattle-area prostate cancer patients. Approximately 30 percent of the study participants reported using statin drugs to control their cholesterol. After a mean follow-up of almost eight years, the researchers found that the risk of death from prostate cancer among statin users was 1 percent as compared to 5 percent for nonusers.

"If the results of our study are validated in other patient cohorts with extended follow-up for cause-specific death, an intervention trial of statin drugs in prostate cancer patients may be justified," Stanford said.

"While statin drugs are relatively well tolerated with a low frequency of serious side effects, they cannot be recommended for the prevention of prostate cancer-related death until a preventive effect on mortality from prostate cancer has been demonstrated in a large, randomized, placebo-controlled clinical trial," said first author Milan S. Geybels, M.Sc., formerly a researcher in Stanford's group who is now based at Maastricht University in The Netherlands.

The study is unique in that most prior research of the impact of statin use on prostate cancer outcomes has focused on biochemical recurrence -- a rising PSA level -- and not prostate cancer-specific mortality. "Very few studies of statin use in relation to death from prostate cancer have been conducted, possibly because such analyses require much longer follow-up for the assessment of this prostate cancer outcome," Geybels said. The potential biological explanation behind the association between statin use and decreased mortality from prostate cancer may be related to cholesterol- and non-cholesterol-mediated mechanisms.

? An example of the former: When cholesterol is incorporated into cell membranes, these "cholesterol-rich domains" play a key role in controlling pathways associated with survival of prostate cancer cells.

? An example of the latter: Statin drugs inhibit an essential precursor to cholesterol production called mevalonate. Lower levels of mevalonate may reduce the risk of fatal prostate cancer.

"Prostate cancer is an interesting disease for which secondary prevention, or preventing poor long-term patient outcomes, should be considered because it is the most common cancer among men in developed countries and the second leading cause of cancer-related deaths," Geybels said. "While many prostate cancer patients have indolent, slow-growing tumors, others have aggressive tumors that may recur or progress to a life-threatening disease despite initial therapy with radiation or surgery. Therefore, any compound that could stop or slow the progression of prostate cancer would be beneficial," he said.

The National Cancer Institute, a grant from the Dutch Cancer Society and additional support from Fred Hutchinson Cancer Research Center and the Prostate Cancer Foundation funded the research.

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Nikon AF-S DX Nikkor 18-55mm f/3.5-5.6G VR

By Jim Fisher

The Nikon AF-S DX Nikkor 18-55mm f/3.5-5.6G VR ($199.95 direct) is the standard kit lens for APS-C Nikon D-SLR cameras. Buying it along with a body halves your out of pocket costs to acquire the lens, but owners of older Nikon D-SLRs bundled with its non-stabilized predecessor may consider it as an upgrade. It produces a field of view that is roughly equivalent to 27-83mm in terms of full-frame photography.

The lens is light at 9.3 ounces and measures just 3.1 by 2.9 inches (HD). It accepts 52mm filters, but the front element does rotate when focus is adjusted, so using a rotating circular polarizing filter can be tricky. Nikon keeps the weight down by using a plastic mount, rather than the more common metal variety, which is more prone to wear and tear over the years. There's an internal focus motor, which is speeider than older screw-drive systems, but because the front element rotates during focus it can be a bit noisy. A bayonet lens hood is available to reduce flare and improve contrast, but is not included?you'll have to spend another $23.50 if you want it.

I used?Imatest?to check the sharpness of that lens when paired with the 24-megapixel D5200. The lens managed a very impressive 2,362 lines per picture height at 18mm f/3.5 using our center-weighted testing method, with edge sharpness hovering around 1,600 lines. We declare an image with an 1,800-line center-weighted score to be acceptably sharp. Stopping down to f/5.6 improves the overall score only marginally to 2,410 lines, but edges sharpen up to 1,850 lines. There is noticeable barrel distortion at 18mm, about 3.3 percent. This will make straight lines noticeably curve outward, and is typical for an 18-55mm design. It can be corrected with software if it distracts from your photos.

Zooming to 35mm narrows the maximum aperture to f/5 and reduces the distortion to a negligible 0.4 percent. The lens scores 2,410 lines here, again with edges around 1,600 lines. Stopping down to f/8 improves overall sharpness to 2,683 lines, with edge sharpness at 2,111 lines. Zoom all the way in to 55mm and the maximum aperture is f/5.6, with an irrelevant 0.2-percent distortion figure. You'll get sharp photos at that setting as well; the lens manages 2,474 lines overall, but is again a little soft at the edges. Stopping down to f/8 improves edge performance to just under 1,800 lines, so your photos will be acceptably sharp from edge to edge.

The Nikon AF-S DX Nikkor 18-55mm f/3.5-5.6G VR is one of the sharpest 18-55mm D-SLR lenses that we've tested, but it's not without its limitations. The narrow aperture limits your ability to shoot in lower light without a flash, and it won't blur the background like an f/2.8 zoom or an f/2 prime lens. It's a good starter lens, but it's one that you'll likely want to upgrade down the road. Nikon offers zoom lenses with longer telephoto reach, like the AF-S DX Nikkor 18-105mm f/3.5-5.6G IF-ED ($399.95), and ones with faster apertures so that you can capture more light like the pro-grade AF-S DX Zoom-Nikkor 17-55mm f/2.8G IF-ED ($1,539.95), but neither are as affordable as this basic 18-55mm optic.

By Jim Fisher Senior Analyst, Digital Cameras

Jim Fisher is the digital camera analyst for the PCMag consumer electronics reviews team. He is a graduate of the Rensselaer Polytechnic Institute, where he concentrated on documentary video production. Jim's interest in photography really...

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Music City mourns country legend George Jones

The casket for country music legend George Jones lies in the Grand Ole Opry House before his funeral on Thursday, May 2, 2013, in Nashville, Tenn. Jones, one of country music's biggest stars who had No. 1 hits in four separate decades, died April 26. He was 81. (AP Photo/Mark Humphrey, Pool)

The casket for country music legend George Jones lies in the Grand Ole Opry House before his funeral on Thursday, May 2, 2013, in Nashville, Tenn. Jones, one of country music's biggest stars who had No. 1 hits in four separate decades, died April 26. He was 81. (AP Photo/Mark Humphrey, Pool)

Patty Loveless embraces Vince Gill, right, after they performed during the funeral for country music star George Jones in the Grand Ole Opry House on Thursday, May 2, 2013, in Nashville, Tenn. Jones, one of country music's biggest stars who had No. 1 hits in four separate decades, died April 26. (AP Photo/Mark Humphrey, Pool)

FILE - In this Jan. 10, 2007 file photo, George Jones is shown in Nashville, Tenn. Jones, the peerless, hard-living country singer who recorded dozens of hits about good times and regrets and peaked with the heartbreaking classic "He Stopped Loving Her Today," has died. He was 81. Jones died Friday, April 26, 2013 at Vanderbilt University Medical Center in Nashville after being hospitalized with fever and irregular blood pressure, according to his publicist Kirt Webster. (AP Photo/Mark Humphrey, file)

Terah Jones, left, comforts her daughter Katie, of Burleson Texas, while waiting to enter the Grand Ole Opry House for the funeral of country music star George Jones on Thursday, May 2, 2013, in Nashville, Tenn. Jones, a country music legend who had No. 1 hits in four separate decades, died April 26. (AP Photo/Mark Zaleski)

Kid Rock speaks during the funeral for country music star George Jones in the Grand Ole Opry House on Thursday, May 2, 2013, in Nashville, Tenn. Jones, one of country music's biggest stars who had No. 1 hits in four separate decades, died April 26. (AP Photo/Mark Humphrey, Pool)

NASHVILLE, Tenn. (AP) ? For a guy who sang so many sad songs, George Jones left behind a lot of laughs.

There was more humor than sadness at Jones' funeral Thursday at the Grand Ole Opry House as thousands gathered in Nashville ? some arriving hours before sunrise ? to pay their respects to the man whose voice has defined country music for more than half a century.

Friend after friend related stories of Jones' kindness, his love for his widow, Nancy, who's credited with helping him survive his personal demons later in life, and the funny little moments that will stick with them always.

Barbara Mandrell remembered the kindnesses he gave a scared 13-year-old girl just getting her start in the business. Former first lady Laura Bush remembered dumping quarter after quarter into the jukebox to hear "The Race Is On." Wynonna Judd remembered his perfect hair and his friendship. And Vince Gill remembered the man who gave him the nickname "Sweet Pea," a moniker he wasn't sure he liked at first but now treasures.

"The great thing is every time someone calls me Sweet Pea, I'll get to think about him," Gill said before earning a standing ovation for his rendition of "Go Rest High on That Mountain" with Patty Loveless.

The nearly 3-hour memorial was attended by several major country stars and political figures. Nancy Jones sat flanked by Bush and Garth Brooks and Trisha Yearwood. Tennessee Gov. Bill Haslam spoke, as did former Arkansas Gov. Mike Huckabee. CBS host Bob Schieffer recalled a 2009 interview with Jones where the singer's true personality seemed to show through.

"I came away feeling his whole life was a surprise to him and he never quite believed any of it," Schieffer said.

Each of the stars who performed had a personal connection to Jones. Randy Travis, who was anointed a traditional country voice by Jones, sang "Amazing Grace," a song Jones had once put his own personal stamp upon.

"When I heard him do this song, it literally gave me chills," Travis said.

Paisley remembered Jones allowing him to house his first horse on the Jones family farm and the visits the two would have, then sang "Me & Jesus." Kid Rock asked Nancy Jones to imagine Jones was actually singing as he performed "Best of Me," before checking himself to the delight of the crowd.

"I know that's a huge (leap of) imagination," Kid Rock said with an embarrassed smile. "Unshaven, long-haired confused country hip-hop rock 'n' roller trying to sing George Jones."

But it may have been Charlie Daniels who summed up Jones best in a long, beautifully rendered tribute. He noted Jones was probably the most imitated country singer of all time.

"George Jones' voice was a rowdy Saturday night uproar at a back-street beer joint, the heartbroken wail of the one who wakes up to find the other side of the bed empty, the far-off lonesome whistle of the midnight train, the look in the eyes of a young bride as that ring is placed on her finger, the memories of a half-asleep old man dreaming about the good old days," Daniels said. "Lost love, lost innocence, good and bad memories, and experiences that are just too much for a human being to deal with. He sang for us all, the non-stop partiers, the guys who are alone and the girl done wrong, the puppy lovers, the extrovert, the introvert and the guy at the end of the bar who never seems to go home ... George had a song for everybody."

The funeral was broadcast live on cable music television channels CMT and GAC and ? in a nod to simpler times when Jones was at his biggest ? on all local television networks.

The Beaumont, Texas, native was in the midst of a farewell tour that was to have wrapped up with an all-star salute in November in Nashville when he died. He postponed two performances two weeks ago and entered the hospital with a fever and irregular blood pressure. He'd been ill off and on over the previous year.

Jones' pure, matchless baritone defined the sound of country music for a half century, and his death brought universal reaction from the music community and fans. Known for hits like "Who's Gonna Fill Their Shoes," ''White Lightning" and "He Stopped Loving Her Today," which Alan Jackson used to close the memorial, Jones had No. 1s in four decades from the 1950s to the 1980s and "Possum" remained a popular figure in Music City until his death.

"Brother George taught us how to sing with a broken heart," Gill said.

Paisley said even though Jones has passed on, his legacy is still there, ready to inspire. He urged young viewers who might be tuning in to check out Jones' music.

"You must be thinking, 'Boy, they're making a ruckus,'" Paisley said. "I would encourage you if you don't know him, go find him now. Go buy his records and see what all this ruckus is about because it's worth it."

___

Follow AP Music Writer Chris Talbott: http://twitter.com/Chris_Talbott.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-05-02-Music-George%20Jones/id-e38def57e66247b3bd8d10999fff834f

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FDA appeals making 'morning-after' pill available to all ages

By Terry Baynes

(Reuters) - The Food and Drug Administration on Wednesday appealed a court order directing the agency to make "morning-after" emergency contraception pills available without a prescription to all girls of reproductive age.

Lawyers with the Justice Department filed the appeal with the 2nd U.S. Circuit Court of Appeals in New York, according to court documents.

The appeal is the latest foray in the years-long legal battle over the pill known as "Plan B," a drug that has also sparked political and religious clashes. If taken up to 120 hours after unprotected sex, it is designed to prevent pregnancy.

The government is seeking to overturn U.S. District Judge Edward Korman's ruling from April 5 that required the FDA to make the emergency contraception available over-the-counter to women of all ages within 30 days.

The Justice Department has asked the district court to temporarily stop its order from taking effect while the appeal is pending, said FDA spokeswoman Erica Jefferson.

The district judge's ruling came in response to a lawsuit originally filed in 2005 by the Center for Reproductive Rights and other groups seeking to strike down age and access limits to the emergency contraception. They argued that there was no scientific proof that girls of reproductive age could not safely use the drug without supervision.

Korman's order reversed a surprise December 2011 decision by U.S. Health and Human Services Secretary Kathleen Sebelius. At the time, the FDA had decided to approve over-the-counter sales with no age limits when Sebelius ordered it to reverse course, barring girls under 17 from buying the pills without a prescription.

President Barack Obama supported that restriction, invoking his daughters. But the timing, 11 months ahead of the presidential election, sparked criticism that he was trying to placate social conservatives.

In his ruling, Korman called Sebelius' decision "arbitrary, capricious and unreasonable."

"The motivation for the secretary's action was obviously political," he wrote.

Nancy Northup, president of the Center for Reproductive Rights, criticized the government's decision to appeal.

Obama's "administration has decided once again to deprive women of their right to obtain emergency contraception without unjustified and burdensome restrictions," she said in a statement.

Before filing its appeal, the FDA said on Tuesday that it would allow girls as young as 15 years old to buy without a prescription the Plan B One-Step emergency contraceptive, made by a unit of Teva Pharmaceutical Industries Ltd.

The agency said its decision to lower the age limit for Plan B One-Step was based on scientific data submitted by Teva that showed girls as young as 15 could safely use the drug without the intervention of a healthcare provider. Cashiers will still have to verify the customer's age before selling it, the FDA said.

The case is Tummino et al. v. Hamburg et al., U.S. District Court for the Eastern District of New York, No. 12-763.

(Reporting by Terry Baynes in New York; Editing by Lisa Shumaker)

Source: http://news.yahoo.com/fda-files-appeal-over-morning-pill-decision-001155986.html

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2 workers removed from Saudi-owned residence

McLEAN, Va. (AP) ? Immigration officials have removed two domestic workers from a northern Virginia home owned by the government of Saudi Arabia as part of an investigation into a report of human trafficking.

Agents went to the home in McLean on Tuesday night, Immigration and Customs Enforcement spokesman Brandon Montgomery said Thursday. Fairfax County police were called in to help.

Montgomery said the investigation is in the early stages. The two women who were removed from the home are from the Philippines, Montgomery said, but there has been no formal determination that they needed to be rescued.

Officials received a tip that alleged two workers were being held in circumstances that amounted to human trafficking, said John Torres, ICE's special agent in charge for Homeland Security Investigations in the Washington field office. But he declined in an interview Thursday to discuss the case in more detail.

ICE is investigating whether there may be other potential victims connected to the home, Torres said. He wouldn't discuss the specific allegations but said that generally in cases of domestic workers, ICE prioritizes those involving allegations of workers being held against their will or threats of violence against workers or their families.

According to real estate records, the Virginia home is owned by the Kingdom of Saudi Arabia's Armed Forces Office. A representative of the Royal Embassy of Saudi Arabia could not be reached for comment Thursday. A guard at the gated home, near the CIA headquarters in Langley, waved off a request to speak to residents there Thursday morning.

At a press briefing Thursday, State Department spokesman Patrick Ventrell said that the agency was aware of the case but that ICE is taking the lead on the investigation. He referred questions there.

Ventrell declined to answer specific questions about whether diplomatic immunity had been invoked. Countries traditionally grant immunity to foreign diplomats to receive reciprocal treatment for their own diplomats and to ensure open lines of communication. Ventrell said that in general, the State Department honors its treaty obligations that provide for immunity while expecting diplomats to observe and respect U.S. laws.

Trafficking cases have been a priority in recent years for the Justice Department, which reports that it has brought an average of 24 cases alleging forced labor in each of the past three fiscal years ? nearly twice as many as the prior period.

Recent cases have involved an Italian government worker at the consulate in San Francisco who was prosecuted in 2011 for keeping a Brazilian woman as an involuntary servant. The same year, a naval officer from the United Arab Emirates was acquitted at a federal trial in Providence, R.I., on charges that he had kept a Filipino woman as an unpaid servant.

Tiffany Williams, an anti-trafficking campaign coordinator for the National Domestic Workers Alliance, works specifically on the issue of diplomats exploiting domestic workers. She said such exploitation can be a particular problem in the diplomatic community because officials know they hold immunity, and it is difficult to punish them.

Generally, though, she said the underlying issue is no different than in cases involving the community at large: The power dynamic is tilted heavily toward the employer. Domestic workers' visas are tied to employment with a particular household, so quitting or standing up to abuse runs the risk of deportation. For domestic workers who live in the home, leaving a job also can mean homelessness, Williams said.

Torres said trafficking cases involving domestic workers are a particular problem in the Washington area, in part because of the presence of a large diplomatic corps and cultural differences ? some countries consider it acceptable to treat workers more harshly than is allowed in the U.S.

To be proactive, Torres said ICE works with nonprofit groups and provides brochures and information to all incoming diplomats who want to bring domestic help from other countries.

Source: http://news.yahoo.com/2-workers-removed-saudi-owned-va-residence-153701708.html

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